Selected papers

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy.

Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, Mawambo GT, Howard JP, Diaz-Marin R, Parinot C, Guber V, Pilon F, Juneau R, Laflamme R, Sawchyn C, Boulay K, Leclerc S, Abu-Thuraia A, Côté JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal JS, Mallette FA, Sapieha P.

Science. 2020 Aug 21;369(6506):eaay5356. doi: 10.1126/science.aay5356.

PMID: 32820093

OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation.

Sharanek A, Burban A, Laaper M, Heckel E, Joyal JS, Soleimani VD, Jahani-Asl A.

Nat Commun. 2020 Aug 17;11(1):4116. doi: 10.1038/s41467-020-17885-z.

PMID: 32807793

Dyslipidemia in retinal metabolic disorders.

Fu Z, Chen CT, Cagnone G, Heckel E, Sun Y, Cakir B, Tomita Y, Huang S, Li Q, Britton W, Cho SS, Kern TS, Hellström A, Joyal JS, Smith LE.

EMBO Mol Med. 2019 Oct;11(10):e10473. doi: 10.15252/emmm.201910473. Epub 2019 Sep 5.

PMID: 31486227

Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.

Joyal JS, Gantner ML, Smith LEH.

Prog Retin Eye Res. 2018 May;64:131-156. doi: 10.1016/j.preteyeres.2017.11.002. Epub 2017 Nov 22. Review. No abstract available.

PMID: 29175509

 

Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.

Joyal JS, Sun Y, Gantner ML, Shao Z, Evans LP, Saba N, et al.

Nat Med. 2016 Apr;22(4):439-45. doi: 10.1038/nm.4059. Epub 2016 Mar 14.

PMID: 26974308

 

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis.

Joyal JS, Nim S, Zhu T, Sitaras N, Rivera JC, Shao Z, et al.

Nat Med. 2014 Oct;20(10):1165-73. doi: 10.1038/nm.3669. Epub 2014 Sep 14.

PMID: 25216639

SOCS3 is an endogenous inhibitor of pathologic angiogenesis.

Stahl A , Joyal JS, Chen J, Sapieha P, Juan A M, et al.

Blood, 2012 Oct 4;120(14):2925-9.

PMID: 22791286

Ischemic neurons prevent vascular regeneration of neural tissue by secreting Semaphorin 3A.

Joyal JS, Sitaras N, Binet F, Rivera JC, Stahl A, et al.

Blood, 2011 Jun 2;117(22):6024-35. 

PMID: 21355092

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life.

Sapieha P, Joyal JS, Rivera JC,  Kermorvant-Duchemin E, Sennlaub F, et al.

J Clin Invest. 2010 Sep 1;120(9):3022-32. Epub 2010 Sep 1.

PMID: 20811158

The succinate receptor GPR91 present on neurons, exerts a major role in retinal angiogenesis.

Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, et al.

Nature Medicine 2008 Oct;14(10):1067-76.

PMID: 18836459